New treatments,
read by a dermatologist

Dermatology is moving quickly right now. These are notes on what is actually emerging — what the data shows, what it does not yet show, and what it may mean for patients — from a double board-certified dermatologist and Mohs surgeon.

• August 19, 2026 Twice Rejected, Now Approved: What an Engineered Virus Means for Advanced Melanoma The FDA has approved an engineered herpes virus injected directly into melanoma tumors, for patients whose disease progressed on PD-1 therapy — after rejecting it twice.
• August 19, 2026 A Mohs Surgeon's Take on the First Phase 3 Win for an mRNA Cancer Vaccine in Melanoma Merck and Moderna report that their personalized mRNA vaccine met its endpoints in a Phase 3 melanoma trial — the first time any cancer vaccine of this kind has done so.
• August 12, 2026 A Mohs Surgeon's Take on Bemotrizinol, the First New U.S. Sunscreen Filter in a Generation NEW YORK — August 12, 2026 — As of last week, American sunscreen manufacturers can legally use an ultraviolet filter that consumers in Europe and Asia have had access to since 1999.…
• August 11, 2026 First-in-Class Oral FASN Inhibitor Denifanstat Could Become the First New Oral Acne Medication in Four Decades, Says New York Dermatologist 11 August 2026 SUMMARY Denifanstat (ASC40), a once-daily oral fatty acid synthase (FASN) inhibitor, met all primary and secondary endpoints in Phase 3 testing and is now advancing…
• April 7, 2026 Low-Dose Isotretinoin Gains Attention as an Emerging Off-Label Anti-Aging Therapy in Dermatology HEADLINE Low-Dose Isotretinoin Gains Attention as an Emerging Off-Label Anti-Aging Therapy in Dermatology SUMMARY Low-dose isotretinoin, traditionally used to treat severe acne, is…
• April 7, 2026 PP-405 Gains Attention as a Novel Small-Molecule Therapy for Hair Loss Following Early Clinical Signals December 4, 2025 HEADLINE PP-405 Gains Attention as a Novel Small-Molecule Therapy for Hair Loss Following Early Clinical Signals SUMMARY PP-405, an investigational topical…
• April 7, 2026 Extended-Release Oral Minoxidil (VDPHL01) Shows Promise as New Treatment for Pattern Hair Loss, Announces New York Dermatologist HEADLINE Extended-Release Oral Minoxidil (VDPHL01) Shows Promise as New Treatment for Pattern Hair Loss, Announces New York Dermatologist SUMMARY VDPHL01, a novel extended-release oral…
• December 4, 2025 New Phase III Data for Breezula® (Clascoterone) Shows Strong Hair-Count Gains and Robust Safety in Androgenetic Alopecia Trials December 4, 2025 HEADLINE New Phase III Data for Breezula® (Clascoterone) Shows Strong Hair-Count Gains and Robust Safety in Androgenetic Alopecia Trials SUMMARY Topical androgen…
• December 4, 2025 Esquire Highlights Breakthrough Hair-Loss Molecule PP-405 as Dermatologists Monitor Emerging Clinical Data December 4, 2025 HEADLINE Esquire Highlights Breakthrough Hair-Loss Molecule PP-405 as Dermatologists Monitor Emerging Clinical Data SUMMARY A recent Esquire article spotlighting the…

These pages are general health information, not medical advice, and reading them does not create a physician–patient relationship. Treatments discussed may be investigational or used off-label and may not be available or appropriate for you. If you are experiencing a medical emergency, call 911 or go to the nearest emergency department.